Doctor's Best Fully Active Folate 800 with Quatrefolic contains Quatrefolic, the (6S)-5-methyltetrahydrofolate glucosamine salt, the most bioavailable form of folate, which provides greater stability and water solubility. Our bodies cannot synthesize folate and due to its water-soluble nature, the body stores folate to a limited extent. Folic acid and dietary folate need to be converted to their metabolically active form to be used by the body. Quatrefolic is metabolically active folate, making it more efficient than folic acid to maximize benefits. Folate helps maintain a healthy prenatal regimen along with a healthy diet and lifestyle. It also helps maintain fetal brain health and spinal column development. Folate is an essential vitamin to support DNA, proper cell division, cardiovascular, mental and emotional well-being. It helps maintain a healthy prenatal regimen along with a healthy diet and lifestyle. Helps support healthy development of the brain and spine of the fetus. Directions for use: Take 1 capsule daily, preferably between meals, or as recommended by a nutritionally informed physician.