Overview If you have relapsed in the past or if you experience cravings while using a single form of Nicotine Replacement Therapy, you can use Nicotinell Combination Therapy to help you stop smoking over several months. The combination of patch and gum is more effective than either product alone in people who have been unable to quit smoking using a single Nicotine Replacement Therapy method, increasing your chances of successfully quitting. When you apply a Nicotinell patch to the skin, nicotine is released and passes into your body through the skin. When you chew Nicotinell gum, nicotine is released and passes into your body through the lining of the mouth. The nicotine obtained from the combination of the patch and the gum will help to gradually reduce the amount of nicotine your body craves each day. Directions For full directions, please read the enclosed instruction leaflet carefully or consult your healthcare professional. Use one Nicotinell patch (nicotine 21mg/24hours) daily.